Determination of the Quinine Content in the Bark of the Cinchona Tree Grown in Mt. Kitanglad, Bukidnon

• Main Authors: Dayrit, Fabian M, Guidote, Armando M, Jr, Generalao, Maximino L, Serna, Constante
• Format: text
• Published: Archīum Ateneo 1994
• Subjects: Chemistry; Other Chemistry
• Online Access: https://archium.ateneo.edu/chemistry-faculty-pubs/53; http://www.herdin.ph/index.php/component/herdin/?view=research&cid=31138
• Institution: Ateneo De Manila University

A rapid, accurate, and inexpensive quantitative HPTLC/densitometry procedure was developed for the simultaneous determination of the four major alkaloids found in the bark of Cinchona species: quinine, quinidine, cinchonine, and cinchonidine. Linearity and % recovery of the procedure were good. This procedure was applied to the analysis of bark samples from seven Cinchona species found in the DENR Cinchona Reforestation Project located in Mt. Kitanglad, Bukidnon: C. calisaya, C. hybrida, C. kartamanah, C. ledgeriana, C. officinalis, C. succirubra, and C. tjinjiroena. The species with the highest % quinine yield were C. ledgeriana, C. officinalis, and C. tjinjiroena.