Feasibility of Cyclodextrin-Potassium Ion Assemblies Synthesis and Its Application in Loading Bio-active Molecules

• Main Authors: PEREZ, YOMKIPPUR, Yu, Gilbert U
• Format: text
• Published: Archīum Ateneo 2020
• Subjects: MOFs; cyclodextrin; busulfan; Chemistry; Organic Chemistry
• Online Access: https://archium.ateneo.edu/chemistry-faculty-pubs/157; https://archium.ateneo.edu/cgi/viewcontent.cgi?article=1156&context=chemistry-faculty-pubs
• Institution: Ateneo De Manila University

In the study, colorless cubic crystals of “green” cyclodextrin (CD)-based assemblies were synthesized and their potential to load bio-active molecules such as drugs and, separately, enzymes were investigated. Busulfan (Bu), an anti-cancer drug widely used to treat chronic myelogenous leukemia (CML),...