Visualizing Phytochemical-Protein Interaction Networks: Momordica charantia and Cancer

• Main Authors: Briones, Yumi L., Young, Alexander T., Dayrit, Fabian M, De Jesus, Armando Jerome, Rojas, Nina Rosario L
• Format: text
• Published: Archīum Ateneo 2021
• Subjects: network visualization; network pharmacology; reverse screening; medicinal plants; phytochemicals; Momordica charantia (bitter gourd); colorectal cancer; Chemistry; Diseases; Oncology; Pharmacology, Toxicology and Environmental Health; Plant Sciences
• Online Access: https://archium.ateneo.edu/chemistry-faculty-pubs/164; https://archium.ateneo.edu/cgi/viewcontent.cgi?article=1163&context=chemistry-faculty-pubs
• Institution: Ateneo De Manila University

The in silico study of medicinal plants is a rapidly growing field. Techniques such as reverse screening and network pharmacology are used to study the complex cellular action of medicinal plants against disease. However, it is difficult to produce a meaningful visualization of phytochemical-protein...