In Silico Evaluation of the Impact of Omicron Variant of Concern Sublineage BA.4 and BA.5 on the Sensitivity of RT-qPCR Assays for SARS-CoV-2 Detection Using Whole Genome Sequencing

In Silico Evaluation of the Impact of Omicron Variant of Concern Sublineage BA.4 and BA.5 on the Sensitivity of RT-qPCR Assays for SARS-CoV-2 Detection Using Whole Genome Sequencing

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VoC) Omicron (B.1.1.529) has rapidly spread around the world, presenting a new threat to global public human health. Due to the large number of mutations accumulated by SARS-CoV-2 Omicron, concerns have emerg...

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Bibliographic Details
Main Authors: Sharma, Divya, Notarte, Kin Israel, Fernandez, Rey Arturo, Lippi, Giuseppe, Gromiha, M. Michael, Henry, Brandon M.
Format: text
Published: Archīum Ateneo 2023
Subjects:
amplicon
BA.4 sublineage
BA.5 sublineage
COVID-19
detection
in silico sensitivity assessment
mismatches
Omicron
primers and probes
RT-qPCR
SARS-CoV-2
substitutions
variant
whole genome sequencing data
Online Access:https://archium.ateneo.edu/gsb-pubs/84
https://doi.org/10.1002/jmv.28241
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Institution: Ateneo De Manila University

Internet

https://archium.ateneo.edu/gsb-pubs/84
https://doi.org/10.1002/jmv.28241

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