Anti-Clastogenic potential of Anthocyanin-Rich Syzygium Curanii L. (Lipote) fruit extract by Erythrocyte Micronucleus Assay in Albino Rats (Rattus Norvegicus).
This study investigated the anti-clastogenic potential of Syzygium curanii L. (lipote) fruit extract by erythrocyte micronucleus assay in rats. Rats were administered with 50mg/kg (low dose) and 100mg/kg (high dose) of lipote fruit extract and were induced with potassium bromate after two weeks....
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
2011
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| Subjects: | |
| Online Access: | http://thesis.dlsud.edu.ph/541/7/MaribbayMendoza%20...%20-%20Anthocyanin.pdf http://thesis.dlsud.edu.ph/541/ |
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| Institution: | De La Salle University |
| Summary: | This study investigated the anti-clastogenic potential of Syzygium curanii L.
(lipote) fruit extract by erythrocyte micronucleus assay in rats. Rats were
administered with 50mg/kg (low dose) and 100mg/kg (high dose) of lipote fruit
extract and were induced with potassium bromate after two weeks. The formation
polychromatic erythrocyte was the base line of the study. The number of
polychromatic erythrocyte was lesser in number in groups administered with
100mg/kg (high dose) of lipote fruit extract compared to the groups exposed to
potassium bromate and not administered with lipote fruit extract. Meanwhile,
groups administered with 100mg/kg (high dose) of lipote fruit extract had lesser
number of polychromatic erythrocyte than that of the group administered with
50mg/kg (low dose) of lipote fruit extract. This means that the lipote fruit extract
inhibited the growth of polychromatic erythrocyte and there was a dose dependent
relationship between the group administered with low dose and high dose of
lipote fruit extract. |
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