Hypocholesteric and anti-obesity effect of anthocyanin-rich syzygium curanii L. lipote fruit extract on male rat fed with a high fat and high cholesterol diet
The main goal of this study was to determine the effect of anthocyaninrich fruit extract from lipote on the male rat fed with high fat and high cholesterol diet. Another goal of this study was to determine the probable decrease in weight, cholesterol in liver and blood. Four groups of male rats,...
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
2011
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| Subjects: | |
| Online Access: | http://thesis.dlsud.edu.ph/545/7/BasilanRosanes%20...%20-%20Anthocyanin.pdf http://thesis.dlsud.edu.ph/545/ |
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| Institution: | De La Salle University |
| Summary: | The main goal of this study was to determine the effect of anthocyaninrich
fruit extract from lipote on the male rat fed with high fat and high cholesterol
diet. Another goal of this study was to determine the probable decrease in weight,
cholesterol in liver and blood. Four groups of male rats, each consisting of four
members, were subjected to the described treatments. The negative control group
(T0) was fed with base diet alone. Treatment groups 2 and 3 (T2 & T3) were fed
the same base diet plus increasing dose of anthocyanin-rich extract from lipote
berries. Lastly, the positive control group (T1) was subjected to the same base diet
plus the sucrose dissolved in drinking water and lard derived from pork fat. The
weight of rats in each treatment group was monitored weekly for four weeks
while the blood and liver cholesterol level were examined post-mortem. Based on
the results of the data, Anthocyanin-rich lipote fruit extract can significantly lower
the cholesterol level in male rat. Statistically there was a significant difference
found in the excessive weight gain of the rat. Moreover, Anthocyanin
significantly decreases the blood and liver cholesterol level in the male rat. |
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