Aging exacerbates damage and delays repair of alveolar epithelia following influenza viral pneumonia

• Main Authors: Yin, Lu, Zheng, Dahai, Limmon, Gino V, Leung, Nicola HN, Xu, Shuoyu, Rajapakse, Jagath C, Hanry, Yu, Chow, Vincent T. K., Chen, Jianzhu
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology
• Online Access: https://hdl.handle.net/10356/100189; http://hdl.handle.net/10220/24081
• Institution: Nanyang Technological University

Background: Influenza virus infection causes significantly higher levels of morbidity and mortality in the elderly. Studies have shown that impaired immunity in the elderly contributes to the increased susceptibility to influenza virus infection, however, how aging affects the lung tissue damage and...