Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING

• Main Authors: Chin, Ko-Hsin, Tu, Zhi-Le, Su, Yi-Che, Yu, Yu-Jen, Chen, Hui-Chen, Lo, Yuan-Chao, Chen, Chin-Pan, Chuah, Mary Lay-Cheng, Liang, Zhao-Xun, Chou, Shan-Ho, Barber, Glen N.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2013
• 主題: DRNTU::Science::Biological sciences
• 在線閱讀: https://hdl.handle.net/10356/100596; http://hdl.handle.net/10220/10980
• 機構: Nanyang Technological University

The mammalian ER protein STING (stimulator of interferon genes; also known as MITA, ERIS, MPYS or TMEM173) is an adaptor protein that links the detection of cytosolic dsDNA to the activation of TANK-binding kinase 1 (TBK1) and its downstream transcription factor interferon regulatory factor 3 (IFN3)...