Electrochemically amplified molecular beacon biosensor for ultrasensitive DNA sequence-specific detection of Legionella sp

• Main Authors: Rai, Varun, Nyine, Yin Thu, Hapuarachchi, Hapuarachchige C., Yap, Hooi Ming, Ng, Lee Ching, Toh, Chee-Seng
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/100767; http://hdl.handle.net/10220/11077
• Institution: Nanyang Technological University

An electrochemically amplified molecular beacon (EAMB) biosensor is constructed using thiolated hairpin DNA-ferrocene probes on gold electrode. The switching from “on” to “off” states of individual probes in the presence of complementary DNA target influences the electrode potential, besides the cur...