Three-dimensional MRI-based computational fluid modeling of the left ventricle for patient before and after surgical ventricular restoration

This study was to simulate the left ventricular (LV) flow in the human heart via combination of computational fluid dynamics (CFD) and magnetic resonance imaging (MRI). MRI was performed for a heart failure (HF) patient before and 4- month after surgical ventricular restoration. The geometry include...

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Main Authors: Khalafvand, Seyed Saeid, Ng, Eddie Yin-Kwee, Zhong, Liang
Other Authors: School of Mechanical and Aerospace Engineering
Format: Conference or Workshop Item
Language:English
Published: 2013
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Online Access:https://hdl.handle.net/10356/100959
http://hdl.handle.net/10220/16760
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1009592020-03-07T13:26:33Z Three-dimensional MRI-based computational fluid modeling of the left ventricle for patient before and after surgical ventricular restoration Khalafvand, Seyed Saeid Ng, Eddie Yin-Kwee Zhong, Liang School of Mechanical and Aerospace Engineering International Conference on Biomedical Engineering and Biotechnology (2012 : Macau) DRNTU::Engineering::Chemical engineering::Biochemical engineering This study was to simulate the left ventricular (LV) flow in the human heart via combination of computational fluid dynamics (CFD) and magnetic resonance imaging (MRI). MRI was performed for a heart failure (HF) patient before and 4- month after surgical ventricular restoration. The geometry included LV, left atrium (LA) and ascending aorta derived for 25 frames during one cycle from MRI data. After reconstruction of time dependent geometries and producing intermediate grids, 3D CFD modeling is performed for both before and after surgery. Intermediate geometries are generated to provide fine enough time steps for CFD modeling and discontinue time step fashion is used. The results showed that velocity of blood in LV increased after surgery and more powerful vortices exist than before surgery LV. Combined CFD/MRI for patients before and after surgery with different heart diseases could facilitate better understanding of flow pattern and research into ways to optimize and refine surgical treatment approaches in the future. 2013-10-24T04:50:08Z 2019-12-06T20:31:27Z 2013-10-24T04:50:08Z 2019-12-06T20:31:27Z 2012 2012 Conference Paper Khalafvand, S. S., Ng, E. Y. K., & Zhong, L. (2012). Three-Dimensional MRI-based Computational Fluid Modeling of the Left Ventricle for Patient before and after Surgical Ventricular Restoration. 2012 International Conference on Biomedical Engineering and Biotechnology (iCBEB), pp.637-640. https://hdl.handle.net/10356/100959 http://hdl.handle.net/10220/16760 10.1109/iCBEB.2012.481 en
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Engineering::Chemical engineering::Biochemical engineering
spellingShingle DRNTU::Engineering::Chemical engineering::Biochemical engineering
Khalafvand, Seyed Saeid
Ng, Eddie Yin-Kwee
Zhong, Liang
Three-dimensional MRI-based computational fluid modeling of the left ventricle for patient before and after surgical ventricular restoration
description This study was to simulate the left ventricular (LV) flow in the human heart via combination of computational fluid dynamics (CFD) and magnetic resonance imaging (MRI). MRI was performed for a heart failure (HF) patient before and 4- month after surgical ventricular restoration. The geometry included LV, left atrium (LA) and ascending aorta derived for 25 frames during one cycle from MRI data. After reconstruction of time dependent geometries and producing intermediate grids, 3D CFD modeling is performed for both before and after surgery. Intermediate geometries are generated to provide fine enough time steps for CFD modeling and discontinue time step fashion is used. The results showed that velocity of blood in LV increased after surgery and more powerful vortices exist than before surgery LV. Combined CFD/MRI for patients before and after surgery with different heart diseases could facilitate better understanding of flow pattern and research into ways to optimize and refine surgical treatment approaches in the future.
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Khalafvand, Seyed Saeid
Ng, Eddie Yin-Kwee
Zhong, Liang
format Conference or Workshop Item
author Khalafvand, Seyed Saeid
Ng, Eddie Yin-Kwee
Zhong, Liang
author_sort Khalafvand, Seyed Saeid
title Three-dimensional MRI-based computational fluid modeling of the left ventricle for patient before and after surgical ventricular restoration
title_short Three-dimensional MRI-based computational fluid modeling of the left ventricle for patient before and after surgical ventricular restoration
title_full Three-dimensional MRI-based computational fluid modeling of the left ventricle for patient before and after surgical ventricular restoration
title_fullStr Three-dimensional MRI-based computational fluid modeling of the left ventricle for patient before and after surgical ventricular restoration
title_full_unstemmed Three-dimensional MRI-based computational fluid modeling of the left ventricle for patient before and after surgical ventricular restoration
title_sort three-dimensional mri-based computational fluid modeling of the left ventricle for patient before and after surgical ventricular restoration
publishDate 2013
url https://hdl.handle.net/10356/100959
http://hdl.handle.net/10220/16760
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