A role for polyamine regulators in ESC self-renewal

• Main Authors: Zhao, Tianyun, Goh, Kim Jee, Ng, Huck Hui, Vardy, Leah A.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/101082; http://hdl.handle.net/10220/11087
• Institution: Nanyang Technological University

Embryonic stem cells (ESCs) depend on extensive regulatory networks to coordinate their self-renewal and differentiation. The polyamine pathway regulator AMD1 was recently implicated in ESC self-renewal and directed differentiation of ESCs to neural precursor cells (NPCs). The polyamines spermine an...