8-Cyclopropyl-2′-Deoxyguanosine: a hole trap for DNA-mediated charge transport

• Main Authors: Wong, Jiun Ru, Shao, Fangwei
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: https://hdl.handle.net/10356/101115; http://hdl.handle.net/10220/19711
• Institution: Nanyang Technological University

DNA duplexes containing 8-cyclopropyl-2′-deoxyguanosine (8CPG) were synthesized to investigate the effect of the C8-modified deoxyguanosine as a kinetic trap for transient hole occupancy on guanines during DNA-mediated hole transport (HT). Thermal denaturation and CD spectra show that DNA duplexes c...