Novel molecular and nanosensors for in vivo sensing

In vivo sensors are an emerging field with the potential to revolutionize our understanding of basic biology and our treatment of disease. In this review, we highlight recent advances in the fields of in vivo electrochemical, optical, and magnetic resonance biosensors with a focus on recent developm...

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Bibliographic Details
Main Authors: Eckert, Mark A., Vu, Priscilla Q., Zhang, Kaixiang, Kang, Dongku, Ali, M. Monsur, Xu, Chenjie, Zhao, Weian
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/101142
http://hdl.handle.net/10220/18312
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Institution: Nanyang Technological University
Language: English
Description
Summary:In vivo sensors are an emerging field with the potential to revolutionize our understanding of basic biology and our treatment of disease. In this review, we highlight recent advances in the fields of in vivo electrochemical, optical, and magnetic resonance biosensors with a focus on recent developments that have been validated in rodent models or human subjects. In addition, we discuss major challenges in the development and translation of in vivo biosensors and present potential solutions to these problems. The field of nanotechnology, in particular, has recently been instrumental in driving the field of in vivo sensors forward. We conclude with a discussion of emerging paradigms and techniques for the development of future biosensors.