Nanopore unstacking of single-stranded DNA helices
Time to unwind: The force-induced unstacking of individual single-stranded homopolymeric DNA helices is demonstrated during their translocation through an -hemolysin protein nanopore by electrophoresis (see picture). The unstacking energy and sequence-specific cooperativity are inferred from an anal...
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| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/101215 http://hdl.handle.net/10220/7494 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Time to unwind: The force-induced unstacking of individual single-stranded homopolymeric DNA helices is demonstrated during their translocation through an -hemolysin protein nanopore by electrophoresis (see picture). The unstacking energy and sequence-specific cooperativity are inferred from an analysis of the translocation kinetics. |
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