Thermoplastic biodegradable elastomers based on ε-caprolactone and L-lactide block copolymers : a new synthetic approach

• Main Authors: Lipik, Vitali T., Kong, Jen Fong, Chattopadhyay, Sujay, Leonardus K. Widjaja, Liow, Sing Shy, Abadie, Marc J. M., Venkatraman, Subbu S.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2011
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: https://hdl.handle.net/10356/101278; http://hdl.handle.net/10220/6837
• Institution: Nanyang Technological University

Although biodegradable polymers have found extensive application in medical devices, there are very few commercially available elastomeric biodegradable polymers. In this work, starting with the well-known monomers L-lactide and ε-caprolactone, we developed elastomers using a multiblock copolymer approach. This ensures that the degradation products of such elastomers are also acceptable from a cytotoxicity standpoint.