CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT

The objective of this study is to find a correlation between the abdominal aortic aneurysm (AAA) geometric parameters, wall stress shear (WSS), abdominal flow patterns, intraluminal thrombus (ILT), and AAA arterial wall rupture using computational fluid dynamics (CFD). Real AAA 3D models were create...

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Main Authors: Ng, E. Y. K., Loong, T. H., Soudah, Eduardo, Bordone, Maurizio, Pua, Uei, Narayanan, Sriram
Other Authors: School of Mechanical and Aerospace Engineering
Format: Article
Language:English
Published: 2014
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Online Access:https://hdl.handle.net/10356/101361
http://hdl.handle.net/10220/18662
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1013612023-03-04T17:18:57Z CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT Ng, E. Y. K. Loong, T. H. Soudah, Eduardo Bordone, Maurizio Pua, Uei Narayanan, Sriram School of Mechanical and Aerospace Engineering DRNTU::Science::Medicine::Computer applications The objective of this study is to find a correlation between the abdominal aortic aneurysm (AAA) geometric parameters, wall stress shear (WSS), abdominal flow patterns, intraluminal thrombus (ILT), and AAA arterial wall rupture using computational fluid dynamics (CFD). Real AAA 3D models were created by three-dimensional (3D) reconstruction of in vivo acquired computed tomography (CT) images from 5 patients. Based on 3D AAA models, high quality volume meshes were created using an optimal tetrahedral aspect ratio for the whole domain. In order to quantify the WSS and the recirculation inside the AAA, a 3D CFD using finite elements analysis was used. The CFD computation was performed assuming that the arterial wall is rigid and the blood is considered a homogeneous Newtonian fluid with a density of 1050 kg/m3 and a kinematic viscosity of 4×10^(-3) Pa·s. Parallelization procedures were used in order to increase the performance of the CFD calculations. A relation between AAA geometric parameters (asymmetry index (β), saccular index (γ), deformation diameter ratio (χ), and tortuosity index (ε)) and hemodynamic loads was observed, and it could be used as a potential predictor of AAA arterial wall rupture and potential ILT formation. Published version 2014-01-21T09:00:32Z 2019-12-06T20:37:11Z 2014-01-21T09:00:32Z 2019-12-06T20:37:11Z 2013 2013 Journal Article Soudah, E., Ng, E. Y. K., Loong, T. H., Bordone, M., Pua, U., & Narayanan, S. (2013). CFD Modelling of Abdominal Aortic Aneurysm on Hemodynamic Loads Using a Realistic Geometry with CT. Computational and Mathematical Methods in Medicine, 2013, 1-9. https://hdl.handle.net/10356/101361 http://hdl.handle.net/10220/18662 10.1155/2013/472564 23864906 en Computational and mathematical methods in medicine © 2013 The Authors. This paper was published in Computational and Mathematical Methods in Medicine and is made available as an electronic reprint (preprint) with permission of the authors. The paper can be found at the following official DOI: [http://dx.doi.org/10.1155/2013/472564]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 10 P. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Science::Medicine::Computer applications
spellingShingle DRNTU::Science::Medicine::Computer applications
Ng, E. Y. K.
Loong, T. H.
Soudah, Eduardo
Bordone, Maurizio
Pua, Uei
Narayanan, Sriram
CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT
description The objective of this study is to find a correlation between the abdominal aortic aneurysm (AAA) geometric parameters, wall stress shear (WSS), abdominal flow patterns, intraluminal thrombus (ILT), and AAA arterial wall rupture using computational fluid dynamics (CFD). Real AAA 3D models were created by three-dimensional (3D) reconstruction of in vivo acquired computed tomography (CT) images from 5 patients. Based on 3D AAA models, high quality volume meshes were created using an optimal tetrahedral aspect ratio for the whole domain. In order to quantify the WSS and the recirculation inside the AAA, a 3D CFD using finite elements analysis was used. The CFD computation was performed assuming that the arterial wall is rigid and the blood is considered a homogeneous Newtonian fluid with a density of 1050 kg/m3 and a kinematic viscosity of 4×10^(-3) Pa·s. Parallelization procedures were used in order to increase the performance of the CFD calculations. A relation between AAA geometric parameters (asymmetry index (β), saccular index (γ), deformation diameter ratio (χ), and tortuosity index (ε)) and hemodynamic loads was observed, and it could be used as a potential predictor of AAA arterial wall rupture and potential ILT formation.
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Ng, E. Y. K.
Loong, T. H.
Soudah, Eduardo
Bordone, Maurizio
Pua, Uei
Narayanan, Sriram
format Article
author Ng, E. Y. K.
Loong, T. H.
Soudah, Eduardo
Bordone, Maurizio
Pua, Uei
Narayanan, Sriram
author_sort Ng, E. Y. K.
title CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT
title_short CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT
title_full CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT
title_fullStr CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT
title_full_unstemmed CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT
title_sort cfd modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with ct
publishDate 2014
url https://hdl.handle.net/10356/101361
http://hdl.handle.net/10220/18662
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