Angiopoietin-like 4 regulates epidermal differentiation

• Main Authors: Mintu Pal, Tan, Ming Jie, Huang, Royston-Luke, Goh, Yan Yih, Wang, Xiao Ling, Tang, Mark Boon Yang, Tan, Nguan Soon
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology
• Online Access: https://hdl.handle.net/10356/101414; http://hdl.handle.net/10220/7135
• Institution: Nanyang Technological University

The nuclear hormone receptor PPARβ/δ is integral to efficient wound re-epithelialization and implicated in epidermal maturation. However, the mechanism underlying the latter process of epidermal differentiation remains unclear. We showed that ligand-activated PPARβ/δ indirectly stimulated keratinocy...