A concise, efficient synthesis of sugar-based benzothiazoles through chemoselective intramolecular C–S coupling

• Main Authors: Shen, Chao, Xia, Haijun, Yan, Hua, Chen, Xinzhi, Ranjit, Sadananda, Xie, Xiaoji, Tan, Davin, Lee, Richmond, Yang, Yanmei, Xing, Bengang, Huang, Kuo-Wei, Zhang, Pengfei, Liu, Xiaogang
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/101575; http://hdl.handle.net/10220/11113
• Institution: Nanyang Technological University

Sugar-based benzothiazoles are a new class of molecules promising for many biological applications. Here, we have synthesized a wide range of sugar-based benzothiazoles from readily accessible glycosyl thioureas by chemoselective, palladium-catalyzed C–S coupling reactions. Corroborated by theoretic...