Impact of host age and parity on susceptibility to severe urinary tract infection in a murine model

• Main Authors: Kline, Kimberly A., Schwartz, Drew J., Gilbert, Nicole M., Lewis, Amanda L.
• Other Authors: Hancock, Lynn E.
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine
• Online Access: https://hdl.handle.net/10356/101691; http://hdl.handle.net/10220/19760
• Institution: Nanyang Technological University

The epidemiology and bacteriology of urinary tract infection (UTI) varies across the human lifespan, but the reasons for these differences are poorly understood. Using established monomicrobial and polymicrobial murine UTI models caused by uropathogenic Escherichia coli (UPEC) and/or Group B Strepto...