Surface modification of PLLA nano-scaffolds with laminin multilayer by LbL assembly for enhancing neurite outgrowth

• Main Authors: He, Liumin, Tang, Shuo, Prabhakaran, Molamma P., Liao, Susan, Tian, Lingling, Zhang, Yuanming, Xue, Wei, Ramakrishna, Seeram
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Materials::Nanostructured materials; DRNTU::Science::Medicine::Biomedical engineering
• Online Access: https://hdl.handle.net/10356/101887; http://hdl.handle.net/10220/19793
• Institution: Nanyang Technological University

In this study, PLLA nanofibers are fabricated by electrospinning and their surfaces are modified by laminin/chitosan (LN/CS) polyelectrolyte multilayer. Surface C/N ratio determined by XPS analysis quantitatively indicates of discrete coating layers on the nanofibers. The amount of LN deposited sust...