A comparison between spray drying and spray freeze drying for dry powder inhaler formulation of drug-loaded lipid–polymer hybrid nanoparticles

• Main Authors: Wang, Yajie, Kho, Katherine, Cheow, Wean Sin, Hadinoto, Kunn
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/101923; http://hdl.handle.net/10220/16906
• Institution: Nanyang Technological University

Lipid–polymer hybrid nanoparticles – polymeric nanoparticles enveloped by lipid layers – have emerged as a potent therapeutic nano-carrier alternative to liposomes and polymeric nanoparticles. Herein we perform comparative studies of employing spray drying (SD) and spray freeze drying (SFD) to produ...