A comparison between spray drying and spray freeze drying for dry powder inhaler formulation of drug-loaded lipid–polymer hybrid nanoparticles

• المؤلفون الرئيسيون: Wang, Yajie, Kho, Katherine, Cheow, Wean Sin, Hadinoto, Kunn
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/101923; http://hdl.handle.net/10220/16906

Lipid–polymer hybrid nanoparticles – polymeric nanoparticles enveloped by lipid layers – have emerged as a potent therapeutic nano-carrier alternative to liposomes and polymeric nanoparticles. Herein we perform comparative studies of employing spray drying (SD) and spray freeze drying (SFD) to produ...