Deformation kinetics of pH-sensitive hydrogels

Polymeric gels can undergo large deformation when subjected to external solutions of varying pH. It is imperative to understand the deformation process of pH-sensitive hydrogels for the effective application of these attractive materials in the biomedical and microfluidic fields. In the modeling of...

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Main Authors: Toh, William, Ng, Teng Yong, Liu, Zishun, Hu, Jianying
Other Authors: School of Mechanical and Aerospace Engineering
Format: Article
Language:English
Published: 2014
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Online Access:https://hdl.handle.net/10356/102241
http://hdl.handle.net/10220/18936
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1022412020-03-07T13:22:14Z Deformation kinetics of pH-sensitive hydrogels Toh, William Ng, Teng Yong Liu, Zishun Hu, Jianying School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering Polymeric gels can undergo large deformation when subjected to external solutions of varying pH. It is imperative to understand the deformation process of pH-sensitive hydrogels for the effective application of these attractive materials in the biomedical and microfluidic fields. In the modeling of these multi-phase materials, finite element (FE) modeling is a useful tool for the development of future applications, and it allows developers to test a wide variety of material responses in a cost-effective and efficient manner, reducing the need to conduct extensive laboratory experiments. Although a FE user-defined material model is available for the equilibrium state, the transient response of pH-sensitive gels has not been effectively modeled. Based on our recent work using the heat transfer analogy to tap into the readily available coupled temperature–displacement elements available in the commercial FE software ABAQUS for simulation of the transient swelling process of neutral hydrogels, the transient swelling process of a pH-sensitive hydrogel is studied and a FE model is further developed to simulate the transient phenomena. Some benchmark examples are investigated to demonstrate the model's capabilities in the simulation of nonlinear deformation kinetics relevant to several applications of pH-sensitive hydrogels. 2014-03-21T06:07:52Z 2019-12-06T20:52:08Z 2014-03-21T06:07:52Z 2019-12-06T20:52:08Z 2013 2013 Journal Article Toh, W., Ng, T. Y., Liu, Z., & Hu, J. (2013). Deformation kinetics of pH-sensitive hydrogels. Polymer International, in press. 0959-8103 https://hdl.handle.net/10356/102241 http://hdl.handle.net/10220/18936 10.1002/pi.4652 en Polymer international © 2013 Society of Chemical Industry.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Engineering::Mechanical engineering
spellingShingle DRNTU::Engineering::Mechanical engineering
Toh, William
Ng, Teng Yong
Liu, Zishun
Hu, Jianying
Deformation kinetics of pH-sensitive hydrogels
description Polymeric gels can undergo large deformation when subjected to external solutions of varying pH. It is imperative to understand the deformation process of pH-sensitive hydrogels for the effective application of these attractive materials in the biomedical and microfluidic fields. In the modeling of these multi-phase materials, finite element (FE) modeling is a useful tool for the development of future applications, and it allows developers to test a wide variety of material responses in a cost-effective and efficient manner, reducing the need to conduct extensive laboratory experiments. Although a FE user-defined material model is available for the equilibrium state, the transient response of pH-sensitive gels has not been effectively modeled. Based on our recent work using the heat transfer analogy to tap into the readily available coupled temperature–displacement elements available in the commercial FE software ABAQUS for simulation of the transient swelling process of neutral hydrogels, the transient swelling process of a pH-sensitive hydrogel is studied and a FE model is further developed to simulate the transient phenomena. Some benchmark examples are investigated to demonstrate the model's capabilities in the simulation of nonlinear deformation kinetics relevant to several applications of pH-sensitive hydrogels.
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Toh, William
Ng, Teng Yong
Liu, Zishun
Hu, Jianying
format Article
author Toh, William
Ng, Teng Yong
Liu, Zishun
Hu, Jianying
author_sort Toh, William
title Deformation kinetics of pH-sensitive hydrogels
title_short Deformation kinetics of pH-sensitive hydrogels
title_full Deformation kinetics of pH-sensitive hydrogels
title_fullStr Deformation kinetics of pH-sensitive hydrogels
title_full_unstemmed Deformation kinetics of pH-sensitive hydrogels
title_sort deformation kinetics of ph-sensitive hydrogels
publishDate 2014
url https://hdl.handle.net/10356/102241
http://hdl.handle.net/10220/18936
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