Design and synthesis of lipidic organoalkoxysilanes for the self-assembly of liposomal nanohybrid cerasomes with controlled drug release properties

• Main Authors: Liang, Xiaolong, Li, Xiaoda, Jing, Lijia, Xue, Peng, Jiang, Lingdong, Ren, Qiushi, Dai, Zhifei
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Chemical engineering::Biochemical engineering
• Online Access: https://hdl.handle.net/10356/102242; http://hdl.handle.net/10220/18939
• Institution: Nanyang Technological University

This paper reports the facile design and synthesis of a series of lipidic organoalkoxysilanes with different numbers of triethoxysilane headgroups and hydrophobic alkyl chains linked by glycerol and pentaerythritol for the construction of cerasomes with regulated surface siloxane density and control...