Gold nanotip array for ultrasensitive electrochemical sensing and spectroscopic monitoring

• Main Authors: Jiang, Yueyue, Meng, Fanben, Qi, Dianpeng, Cai, Pingqiang, Yin, Zongyou, Shao, Fangwei, Zhang, Hua, Boey, Freddy Yin Chiang, Chen, Xiaodong
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Chemistry::Analytical chemistry
• Online Access: https://hdl.handle.net/10356/102369; http://hdl.handle.net/10220/19017
• Institution: Nanyang Technological University

A gold nanotip array platform with a combination of ultrasensitive electrochemical sensing and spectroscopic monitoring capability is reported. Adenosine triphosphate is detected down to 1 pM according to the impedance changes in response to aptamer-specific binding. Furthermore, the local molecular information can be monitored at the individual plasmonic nanotips, and hence provide the capability for a better understanding of complex biological processes.