Evaluating the toxicity of hydroxyapatite nanoparticles in catfish cells and zebrafish embryos

• Main Authors: Zhao, Xinxin, Ong, Kimberly J., Ede, James D., Stafford, James L., Ng, Kee Woei, Goss, Greg G., Loo, Joachim Say Chye
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Materials
• Online Access: https://hdl.handle.net/10356/102450; http://hdl.handle.net/10220/18981
• Institution: Nanyang Technological University

The toxicity of needle-(nHA-ND) and rod-shaped (nHA-RD) hydroxyapatite (HA) nanoparticles is evaluated in vitro on catfish B-cells (3B11) and catfish T-cells (28s.3) and in vivo on zebrafish embryos to determine if biological effects are similar to the effects seen in mammalian in vitro systems. Nei...