Digging deep into Golgi phenotypic diversity with unsupervised machine learning

• المؤلفون الرئيسيون: Wang, Yi, Huang, Dong, Bard, Frederic, Ke, Yiping, Lee, Kee Khoon, Hussain, Shaista, Le Guezennec, Xavier, Chia, Joanne
• مؤلفون آخرون: Sommer, Thomas
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Golgi; Phenotypic Diversity; DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/102613; http://hdl.handle.net/10220/47249

The synthesis of glycans and the sorting of proteins are critical functions of the Golgi apparatus and depend on its highly complex and compartmentalized architecture. High-content image analysis coupled to RNA interference screening offers opportunities to explore this organelle organization and th...