Development of a novel biodegradable drug-eluting ventilation tube for chronic otitis media with effusion

• Main Authors: Wong, Yee Shan, Venkatraman, Subbu S., Gan, Chee Wee, Chooi, Wai Hon, Ng, Anthony Herr Cheun, Lim, Lynne Hsueh Yee
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: https://hdl.handle.net/10356/102817; http://hdl.handle.net/10220/19160
• Institution: Nanyang Technological University

Objectives/Hypothesis: To develop a novel drug-eluting biodegradable ventilation tube (VT), to evaluate in vitro sustained release and antibacterial adherence of ofloxacin-loaded biodegradable VT on Pseudomonas aeruginosa, and to evaluate in vivo biodegradation of VT in guinea pig ears. Study Design...