Enzyme-responsive cell-penetrating peptides conjugated mesoporous silica quantum dots nanocarriers for controlled release of nucleus-targeted drug molecules and real-time intracellular fluorescence imaging of tumor cells

• Main Authors: Costa, Marianne, Yeow, Edwin K. L., Li, Jinming, Liu, Fang, Shao, Qing, Min, Yuanzeng, Xing, Bengang
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2014
• 主題: DRNTU::Science::Chemistry::Biochemistry
• 在線閱讀: https://hdl.handle.net/10356/102852; http://hdl.handle.net/10220/19217
• 機構: Nanyang Technological University

Here, a set of novel and personalized nanocarriers are presented for controlled nucleus-targeted antitumor drug delivery and real-time imaging of intracellular drug molecule trafficking by integrating an enzyme activatable cell penetrating peptide (CPP) with mesoporous silica coated quantum dots nan...