Subcutaneous tissue response to titanium, poly(ϵ-caprolactone), and carbonate-substituted hydroxyapatite-coated poly(ϵ-caprolactone) plates : a rabbit study

• Main Authors: Chanchareonsook, Nattharee, Tideman, Henk, Feinberg, Stephen E., Hollister, Scott J., Jongpaiboonkit, Leenaporn, Kin, Liao, Jansen, John A.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering::Chemical engineering
• Online Access: https://hdl.handle.net/10356/102919; http://hdl.handle.net/10220/19134
• Institution: Nanyang Technological University

The aim of this study was to evaluate the soft tissue response to poly(ϵ-caprolactone) (PCL) implants with and without carbonate-substituted hydroxyapatite (CHA) coating compared to the commonly used titanium alloy (Ti-6Al-4V)-machined surface. Experimental materials were implanted subcutaneously in...