Decreased endothelial nitric oxide bioavailability, impaired microvascular function, and increased tissue oxygen consumption in children with falciparum malaria

• Main Authors: Yeo, Tsin W., Lampah, Daniel A., Kenangelem, Enny, Tjitra, Emiliana, Weinberg, J. Brice, Granger, Donald L., Price, Ric N., Anstey, Nicholas M.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology::Human anatomy
• Online Access: https://hdl.handle.net/10356/102959; http://hdl.handle.net/10220/24404
• Institution: Nanyang Technological University

Endothelial nitric oxide (NO) bioavailability, microvascular function, and host oxygen consumption have not been assessed in pediatric malaria. We measured NO-dependent endothelial function by using peripheral artery tonometry to determine the reactive hyperemia index (RHI), and microvascular functi...