De Novo Generated Human Red Blood Cells in Humanized Mice Support Plasmodium falciparum Infection

• Main Authors: Amaladoss, Anburaj, Chen, Qingfeng, Liu, Min, Dummler, Sara K., Dao, Ming, Suresh, Subra, Chen, Jianzhu, Preiser, Peter R.
• 其他作者: Marinho, Claudio Romero Farias
• 格式: Article
• 語言: English
• 出版: 2015
• 在線閱讀: https://hdl.handle.net/10356/103060; http://hdl.handle.net/10220/38703

Immunodeficient mouse–human chimeras provide a powerful approach to study host specific pathogens like Plasmodium (P.) falciparum that causes human malaria. Existing mouse models of P. falciparum infection require repeated injections of human red blood cells (RBCs). In addition, clodronate lipsomes...