Review of diverse optical fibers used in biomedical research and clinical practice

Optical fiber technology has significantly bolstered the growth of photonics applications in basic life sciences research and in biomedical diagnosis, therapy, monitoring, and surgery. The unique operational characteristics of diverse fibers have been exploited to realize advanced biomedical functio...

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Main Authors: Shum, Perry Ping, Keiser, Gerd, Xiong, Fei, Cui, Ying
Other Authors: School of Electrical and Electronic Engineering
Format: Article
Language:English
Published: 2015
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Online Access:https://hdl.handle.net/10356/103085
http://hdl.handle.net/10220/25804
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1030852020-09-26T22:04:17Z Review of diverse optical fibers used in biomedical research and clinical practice Shum, Perry Ping Keiser, Gerd Xiong, Fei Cui, Ying School of Electrical and Electronic Engineering Research Techno Plaza DRNTU::Science::Medicine::Optical instruments Optical fiber technology has significantly bolstered the growth of photonics applications in basic life sciences research and in biomedical diagnosis, therapy, monitoring, and surgery. The unique operational characteristics of diverse fibers have been exploited to realize advanced biomedical functions in areas such as illumination, imaging, minimally invasive surgery, tissue ablation, biological sensing, and tissue diagnosis. This review paper provides the necessary background to understand how optical fibers function, to describe the various categories of available fibers, and to illustrate how specific fibers are used for selected biomedical photonics applications. Research articles and vendor data sheets were consulted to describe the operational characteristics of conventional and specialty multimode and single-mode solid-core fibers, double-clad fibers, hard-clad silica fibers, conventional hollow-core fibers, photonic crystal fibers, polymer optical fibers, side-emitting and side-firing fibers, middle-infrared fibers, and optical fiber bundles. Representative applications from the recent literature illustrate how various fibers can be utilized in a wide range of biomedical disciplines. In addition to helping researchers refine current experimental setups, the material in this review paper will help conceptualize and develop emerging optical fiber-based diagnostic and analysis tools. Published version 2015-06-07T04:39:27Z 2019-12-06T21:05:16Z 2015-06-07T04:39:27Z 2019-12-06T21:05:16Z 2014 2014 Journal Article Keiser, G., Xiong, F., Cui, Y., & Shum, P. P. (2014). Review of diverse optical fibers used in biomedical research and clinical practice. Journal of biomedical optics, 19(8), 080902-. 1083-3668 https://hdl.handle.net/10356/103085 http://hdl.handle.net/10220/25804 10.1117/1.JBO.19.8.080902 en Journal of biomedical optics © 2014 Society of Photo-optical Instrumentation Engineers (SPIE). This paper was published in Journal of Biomedical Optics and is made available as an electronic reprint (preprint) with permission of Society of Photo-optical Instrumentation Engineers (SPIE). The paper can be found at the following official DOI: [http://dx.doi.org/10.1117/1.JBO.19.8.080902]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Science::Medicine::Optical instruments
spellingShingle DRNTU::Science::Medicine::Optical instruments
Shum, Perry Ping
Keiser, Gerd
Xiong, Fei
Cui, Ying
Review of diverse optical fibers used in biomedical research and clinical practice
description Optical fiber technology has significantly bolstered the growth of photonics applications in basic life sciences research and in biomedical diagnosis, therapy, monitoring, and surgery. The unique operational characteristics of diverse fibers have been exploited to realize advanced biomedical functions in areas such as illumination, imaging, minimally invasive surgery, tissue ablation, biological sensing, and tissue diagnosis. This review paper provides the necessary background to understand how optical fibers function, to describe the various categories of available fibers, and to illustrate how specific fibers are used for selected biomedical photonics applications. Research articles and vendor data sheets were consulted to describe the operational characteristics of conventional and specialty multimode and single-mode solid-core fibers, double-clad fibers, hard-clad silica fibers, conventional hollow-core fibers, photonic crystal fibers, polymer optical fibers, side-emitting and side-firing fibers, middle-infrared fibers, and optical fiber bundles. Representative applications from the recent literature illustrate how various fibers can be utilized in a wide range of biomedical disciplines. In addition to helping researchers refine current experimental setups, the material in this review paper will help conceptualize and develop emerging optical fiber-based diagnostic and analysis tools.
author2 School of Electrical and Electronic Engineering
author_facet School of Electrical and Electronic Engineering
Shum, Perry Ping
Keiser, Gerd
Xiong, Fei
Cui, Ying
format Article
author Shum, Perry Ping
Keiser, Gerd
Xiong, Fei
Cui, Ying
author_sort Shum, Perry Ping
title Review of diverse optical fibers used in biomedical research and clinical practice
title_short Review of diverse optical fibers used in biomedical research and clinical practice
title_full Review of diverse optical fibers used in biomedical research and clinical practice
title_fullStr Review of diverse optical fibers used in biomedical research and clinical practice
title_full_unstemmed Review of diverse optical fibers used in biomedical research and clinical practice
title_sort review of diverse optical fibers used in biomedical research and clinical practice
publishDate 2015
url https://hdl.handle.net/10356/103085
http://hdl.handle.net/10220/25804
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