Cross-reactivity and anti-viral function of dengue capsid and NS3-specific memory T cells toward Zika virus

Cross-reactivity and anti-viral function of dengue capsid and NS3-specific memory T cells toward Zika virus

Zika virus (ZIKV), a flavivirus with homology to dengue virus (DENV), is spreading to areas of DENV hyper-endemicity. Heterologous T cell immunity, whereby virus-specific memory T cells are activated by variant peptides derived from a different virus, can lead to enhanced viral clearance or diminish...

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Bibliographic Details
Main Authors: Lye, David Chienboon, Lim, Mei Qiu, Kumaran, Emmanuelle A. P., Tan, Hwee Cheng, Leo, Yee Sin, Ooi, Eng Eong, MacAry, Paul A., Bertoletti, Antonio, Rivino, Laura
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2019
Subjects:
Zika Virus (ZIKV)
Dengue Virus (DENV)
DRNTU::Science::Medicine
Online Access:https://hdl.handle.net/10356/103398
http://hdl.handle.net/10220/47310
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/103398
http://hdl.handle.net/10220/47310

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