A predictor for predicting Escherichia coli transcriptome and the effects of gene perturbations

• Main Authors: Poh, Chueh Loo, Ling, Maurice H. T.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine::Biomedical engineering
• Online Access: https://hdl.handle.net/10356/103536; http://hdl.handle.net/10220/20004
• Institution: Nanyang Technological University

Background A means to predict the effects of gene over-expression, knockouts, and environmental stimuli in silico is useful for system biologists to develop and test hypotheses. Several studies had predicted the expression of all Escherichia coli genes from sequences and reported a correlation of 0...