Precursory signatures of protein folding/unfolding : from time series correlation analysis to atomistic mechanisms

• Main Authors: Hsu, P. J., Cheong, S. A., Lai, S. K.
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science
• Online Access: https://hdl.handle.net/10356/103714; http://hdl.handle.net/10220/20018
• Institution: Nanyang Technological University

Folded conformations of proteins in thermodynamically stable states have long lifetimes. Before it folds into a stable conformation, or after unfolding from a stable conformation, the protein will generally stray from one random conformation to another leading thus to rapid fluctuations. Brief struc...