Antimicrobial quaternary ammonium organosilane cross-linked nanofibrous collagen scaffolds for tissue engineering

• Main Authors: Dhand, Chetna, Balakrishnan, Yamini, Ong, Seow Theng, Dwivedi, Neeraj, Venugopal, Jayarama R., Harini, Sriram, Leung, Chak Ming, Low, Kenny Zhi Wei, Loh, Xian Jun, Beuerman, Roger W., Ramakrishna, Seeram, Verma, Navin Kumar, Lakshminarayanan, Rajamani
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2019
• Subjects: DRNTU::Science::Medicine; Anti-infective Wound Dressing; Cyto-compatible Nanofibre
• Online Access: https://hdl.handle.net/10356/103718; http://hdl.handle.net/10220/47368
• Institution: Nanyang Technological University

Introduction: In search for cross-linkers with multifunctional characteristics, the present work investigated the utility of quaternary ammonium organosilane (QOS) as a potential cross-linker for electrospun collagen nanofibers. We hypothesized that the quaternary ammonium ions improve the electrosp...