Hydrogen sulfide is an endogenous regulator of aging in Caenorhabditis elegans

• Main Authors: Qabazard, Bedoor, Li, Ling, Gruber, Jan, Peh, Meng Teng, Ng, Li Fang, Dinesh Kumar, Srinivasan, Rose, Peter, Tan, Choon-Hong, Dymock, Brian W., Wei, Feng, Swain, Suresh C., Halliwell, Barry, Stürzenbaum, Stephen R., Moore, Philip K.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine
• Online Access: https://hdl.handle.net/10356/103725; http://hdl.handle.net/10220/19282
• Institution: Nanyang Technological University

Aims: To investigate the role of endogenous hydrogen sulfide (H2S) in the control of aging and healthspan of Caenorhabditis elegans. Results: We show that the model organism, C. elegans, synthesizes H2S. Three H2S-synthesizing enzymes are present in C. elegans, namely cystathionine γ lyase (CSE), cy...