In-frame and unmarked gene deletions in burkholderia cenocepacia via an allelic exchange system compatible with gateway technology

• Main Authors: Fazli, Mustafa, Harrison, Joe J., Gambino, Michela, Givskov, Michael, Tolker-Nielsen, Tim
• Other Authors: Schottel, J. L.
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Microbiology
• Online Access: https://hdl.handle.net/10356/103759; http://hdl.handle.net/10220/25853
• Institution: Nanyang Technological University

Burkholderia cenocepacia is an emerging opportunistic pathogen causing life-threatening infections in immunocompromised individuals and in patients with cystic fibrosis, which are often difficult, if not impossible, to treat. Understanding the genetic basis of virulence in this emerging pathogen is...