Cobalt-catalyzed chelation-assisted alkylation of arenes with primary and secondary alkyl halides

• المؤلفون الرئيسيون: Gao, Ke, Yamakawa, Takeshi, Yoshikai, Naohiko
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Chemistry::Organic chemistry
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/103795; http://hdl.handle.net/10220/24559
• المؤسسة: Nanyang Technological University

Cobalt–N-heterocyclic carbene catalytic systems have been developed for chelation-assisted ortho-alkylation of aromatic compounds with alkyl halides. Aryl imines can be selectively monoalkylated at room temperature by various primary or secondary alkyl chlorides or bromides. The catalytic system can...