Single-layer transition metal dichalcogenide nanosheet-based nanosensors for rapid, sensitive, and multiplexed detection of DNA

• Main Authors: Zhang, Ying, Zheng, Bing, Zhu, Changfeng, Zhang, Xiao, Tan, Chaoliang, Li, Hai, Chen, Bo, Yang, Jian, Chen, Junze, Huang, Ying, Wang, Lianhui, Zhang, Hua
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Engineering::Materials::Nanostructured materials
• Online Access: https://hdl.handle.net/10356/103852; http://hdl.handle.net/10220/24624
• Institution: Nanyang Technological University

Single-layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence-quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a single-layer TaS2 nanosheet-based multiplexed DNA sensor is also developed.