A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells

A multifunctional probe aggregation-induced emission-Zinc(II)-dipicolylamine (AIE-ZnDPA) is developed for selective targeting, fluorescence imaging, and photodynamic killing of both Gram-positive and Gram-negative bacteria over mammalian cells. The probe has significant advantages in simple probe de...

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Main Authors: Gao, Meng, Hu, Qinglian, Feng, Guangxue, Tomczak, Nikodem, Liu, Rongrong, Xing, Bengang, Tang, Ben Zhong, Liu, Bin
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/103972
http://hdl.handle.net/10220/24622
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1039722020-03-07T12:34:54Z A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells Gao, Meng Hu, Qinglian Feng, Guangxue Tomczak, Nikodem Liu, Rongrong Xing, Bengang Tang, Ben Zhong Liu, Bin School of Physical and Mathematical Sciences DRNTU::Engineering::Materials A multifunctional probe aggregation-induced emission-Zinc(II)-dipicolylamine (AIE-ZnDPA) is developed for selective targeting, fluorescence imaging, and photodynamic killing of both Gram-positive and Gram-negative bacteria over mammalian cells. The probe has significant advantages in simple probe design, enhanced fluorescence upon bacteria binding, excellent photostability, and broad-spectrum antibacterial activity with almost no harm to mammalian cells. 2015-01-15T02:53:07Z 2019-12-06T21:23:43Z 2015-01-15T02:53:07Z 2019-12-06T21:23:43Z 2014 2014 Journal Article Gao, M., Hu, Q., Feng, G., Tomczak, N., Liu, R., Xing, B., et al. (2014). A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells. Advanced healthcare materials, 4(5), 659-663. 2192-2640 https://hdl.handle.net/10356/103972 http://hdl.handle.net/10220/24622 10.1002/adhm.201400654 en Advanced healthcare materials © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Engineering::Materials
spellingShingle DRNTU::Engineering::Materials
Gao, Meng
Hu, Qinglian
Feng, Guangxue
Tomczak, Nikodem
Liu, Rongrong
Xing, Bengang
Tang, Ben Zhong
Liu, Bin
A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells
description A multifunctional probe aggregation-induced emission-Zinc(II)-dipicolylamine (AIE-ZnDPA) is developed for selective targeting, fluorescence imaging, and photodynamic killing of both Gram-positive and Gram-negative bacteria over mammalian cells. The probe has significant advantages in simple probe design, enhanced fluorescence upon bacteria binding, excellent photostability, and broad-spectrum antibacterial activity with almost no harm to mammalian cells.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Gao, Meng
Hu, Qinglian
Feng, Guangxue
Tomczak, Nikodem
Liu, Rongrong
Xing, Bengang
Tang, Ben Zhong
Liu, Bin
format Article
author Gao, Meng
Hu, Qinglian
Feng, Guangxue
Tomczak, Nikodem
Liu, Rongrong
Xing, Bengang
Tang, Ben Zhong
Liu, Bin
author_sort Gao, Meng
title A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells
title_short A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells
title_full A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells
title_fullStr A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells
title_full_unstemmed A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells
title_sort multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells
publishDate 2015
url https://hdl.handle.net/10356/103972
http://hdl.handle.net/10220/24622
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