Selective susceptibility of human skin antigen presenting cells to productive dengue virus infection

• Main Authors: Cerny, Daniela, Haniffa, Muzlifah, Shin, Amanda, Bigliardi, Paul, Tan, Bien Keem, Lee, Bernett, Poidinger, Michael, Tan, Ern Yu, Ginhoux, Florent, Fink, Katja
• Other Authors: Kuhn, Richard J.
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Bacteria
• Online Access: https://hdl.handle.net/10356/104006; http://hdl.handle.net/10220/24602
• Institution: Nanyang Technological University

Dengue is a growing global concern with 390 million people infected each year. Dengue virus (DENV) is transmitted by mosquitoes, thus host cells in the skin are the first point of contact with the virus. Human skin contains several populations of antigen-presenting cells which could drive the immune...