Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

• المؤلفون الرئيسيون: Hansen, Christine Rønne, Liengaard, Lars, Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus, Kharazmi, Arsalan, Pressler, Tanja, Høiby, Niels, Jensen, Peter Østrup
• مؤلفون آخرون: Gulbins, Erich
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Medicine
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/104137; http://hdl.handle.net/10220/19555
• المؤسسة: Nanyang Technological University

Chronic lung infection by Pseudomonas aeruginosa is the major severe complication in cystic fibrosis (CF) patients, where P. aeruginosa persists and grows in biofilms in the endobronchial mucus under hypoxic conditions. Numerous polymorphonuclear leukocytes (PMNs) surround the biofilms and create lo...