Distinctive molecular signature and activated signaling pathways in aortic smooth muscle cells of patients with myocardial infarction

• Main Authors: Wongsurawat, Thidathip, Woo, Chin Cheng, Giannakakis, Antonis, Lin, Xiao Yun, Cheow, Esther Sok Hwee, Lee, Chuen Neng, Richards, Mark, Sze, Siu Kwan, Nookaew, Intawat, Kuznetsov, Vladimir Andreevich, Sorokin, Vitaly
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: Myocardial Infarction; DRNTU::Science::Biological sciences; Vascular Smooth Muscle Cells
• Online Access: https://hdl.handle.net/10356/104138; http://hdl.handle.net/10220/47805
• Institution: Nanyang Technological University

Background and aims: We aim to identify significant transcriptome alterations of vascular smooth muscle cells (VSMCs) in the aortic wall of myocardial infarction (MI) patients. Providing a robust transcriptomic signature, we aim to highlight the most likely aberrant pathway(s) in MI VSMCs. Methods a...