Organ-on-e-chip : three-dimensional self-rolled biosensor array for electrical interrogations of human electrogenic spheroids

• Main Authors: Kalmykov, Anna, Huang, Changjin, Bliley, Jacqueline, Shiwarski, Daniel, Tashman, Joshua, Rastogi, Sahil K., Shukla, Shivani, Mataev, Elnatan, Feinberg, Adam W., Hsia, K. Jimmy, Cohen-Karni, Tzahi, Arif Abdullah
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Electrical; Science::Biological sciences; Spheroids
• Online Access: https://hdl.handle.net/10356/104260; http://hdl.handle.net/10220/49992
• Institution: Nanyang Technological University

Cell-cell communication plays a pivotal role in coordination and function of biological systems. Three-dimensional (3D) spheroids provide venues to explore cellular communication for tissue development and drug discovery, as their 3D architecture mimics native in vivo microenvironments. Cellular ele...