Integration of multiple data sources to prioritize candidate genes using discounted rating system

• Main Authors: Li, Yongjin, Patra, Jagdish Chandra
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2011
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• Online Access: https://hdl.handle.net/10356/104604; http://hdl.handle.net/10220/7087
• Institution: Nanyang Technological University

Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their similarity to known disease genes. Most of existing gene prioritization methods access only one genomic data source, which is noisy and in...