Pushing the envelope in tissue engineering : ex vivo production of thick vascularized cardiac ECM constructs

• Main Authors: Venkatraman, Subbu S., Machluf, Marcelle, Sarig, Udi, Nguyen, Evelyne Bao-Vi, Wang, Yao, Ting, Sherwin, Bronshtein, Tomer, Sarig, Hadar, Dahan, Nitsan, Gvirtz, Maskit, Reuveny, Shaul, Oh, Steve K.W., Scheper, Thomas, Boey, Yin Chiang Freddy
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Medicine::Tissue engineering
• Online Access: https://hdl.handle.net/10356/104653; http://hdl.handle.net/10220/25922
• Institution: Nanyang Technological University

Functional vascularization is a prerequisite for cardiac tissue engineering of constructs with physiological thicknesses. We previously reported the successful preservation of main vascular conduits in isolated thick acellular porcine cardiac ventricular ECM (pcECM). We now unveil this scaffold'...