Rapid discovery of the potential toxic compounds in Polygonum multiflorum by UHPLC/Q-Orbitrap-MS-based metabolomics and correlation analysis

• المؤلفون الرئيسيون: Han, Lifeng, Wang, Piao, Wang, Yulan, Zhao, Qianyu, Zheng, Fang, Dou, Zhiying, Yang, Wenzhi, Hu, Limin, Liu, Caixiang
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2019
• الموضوعات: Metabolomics; Polygonum Multiflorum; DRNTU::Science::Medicine
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/104728; http://hdl.handle.net/10220/48641
• المؤسسة: Nanyang Technological University

The dry roots of Polygonum multiflorum (PM), involving both the raw and processed materials, are widely used as the traditional Chinese medicine for treating various diseases in China. Hepatotoxicity has been occasionally reported in patients who consume PM. Unfortunately, no definite criteria are c...