Alzheimer’s disease : a panorama glimpse

• Main Authors: Zhao, Li Na, Mu, Yuguang, Lu, Lanyuan, Chew, Lock Yue
• Other Authors: School of Computer Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/104759; http://hdl.handle.net/10220/20291
• Institution: Nanyang Technological University

The single-mutation of genes associated with Alzheimer’s disease (AD) increases the production of Aβ peptides. An elevated concentration of Aβ peptides is prone to aggregation into oligomers and further deposition as plaque. Aβ plaques and neurofibrillary tangles are two hallmarks of AD. In this rev...